High-Performance NIR-II In Vivo Preclinical Imaging

Deep-Tissue Penetration, Zero Autofluorescence, and Real-Time Multiplexed Quantification

The IR VIVO™ preclinical imaging system opens an unprecedented window into living bodies by fully exploiting the short-wave infrared spectrum (NIR-II / SWIR, 700–1600 nm). Operating where biological tissues become highly transparent, this reference platform dramatically minimizes light scattering and completely eliminates background autofluorescence. Powered by Photon etc.’s ultra-low noise Alizé 1.7 deep-cooled InGaAs camera (operating at -60 °C) and paired with highly intense laser illumination sources , IR VIVO™ delivers unmatched optical sensitivity and a superior signal-to-noise ratio down to depths of 2 cm.

It provides researchers with a non-destructive, high-contrast tool to visualize features—such as the brain through intact bone or black melanoma—that are completely hidden from traditional visible and NIR-I instruments.

A Growing Spectrum of Solutions

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Engineered to accelerate discoveries across a diverse suite of advanced preclinical applications

Fluorescence Guided Surgery (FGS) & Resection

Achieves binary, unambiguous tumor delineation to drastically minimize the risk of missed malignant residues compared to NIR-I imaging.

Vascularization & Lymphatic Tracking

Maps microvascular structures, angiogenesis, lymph nodes, and real-time lymphatic drainage with crystal clarity.

Fluorescent Label Multiplexing

Simultaneously tracks distinct anatomical and molecular signals within the same model by isolating different emission bandwidths across the NIR-II window.

Multiplexing

Reg : Zhong et al, Multiplexed Short-wave Infrared Imaging Highlights Anatomical Structures in Mice, bioRxiv

Multiplexing Capabilities

Lymphatic and Vascular Signals in the Same Mouse and Different Emission Bandwidths in the NIR-II Region.

Technical Specifications

Technical Specifications

Emission spectral range

700–1600 nm

Technical Specifications

Imaging modes

Fluorescence, reflectance, overlay

Technical Specifications

Emission filters

Jusqu’à 10 canaux d’émission

Technical Specifications

Illumination source

Laser at 670, 760, 808 and 890 nm

and adjustable power density

Technical Specifications

Lens

50mm f/1.4 lens

Technical Specifications

Field of view

80 x 64 mm to 50 x 40mm

Variable FOV for 1 mouse or individual organ view

Technical Specifications

Stage

Manual XY and motorize Z

Technical Specifications

Dimensions

(L x W x H)

77 × 60 × 98 cm

Technical Specifications

Camera type

InGaAs (Alizé™ 1.7)

In Vivo NIR-II Imaging: Contact-Free Monitoring Heartbeat & Respiratory Rate

High-speed imaging made available by the fast frame rates of InGaAs cameras allows for contact-free cardiography and respiratory rate measurements in both anesthetized and awake animals. Such contact-free measurements of awake mice obtained without the use of any restraining device could drastically change studies procedures in labs.

IR VIVO Guided Tour

IR VIVO is an infrared multispectral imager for small animal studies. This system benefits from reduced light scattering, absorption and auto-fluorescence by using a detection system in the near and short-wave infrared. Visualize your biomarkers in vivo and in real-time with optimized contrast resolution and sensitivity. IR VIVO takes advantage of the most recent developments in SWIR imaging with an ultra-low-noise InGaAs camera (Alizé 1.7 or ZephIR 1.7), novel homogeneous illumination and powerful analytical software to provide an unprecedented combination of fast, high resolution and deep imaging.

Custom Products

Beyond our standard product lines, we bring to bear our know-how through collaborations with industry and researchers both local and international.

It’s in our DNA to build systems that measure up to the high standards set by our customers in science and industry.

Visit our Special Projects page or contact us if you can’t find what you’re looking for in our standard product lines.