Open near infrared fluorescence imaging
The LightIR is an open fluorescence imaging device designed for preclinical fluorescence imaging or clinical research.
The LightIR™ is a state-of-the-art in vivo fluorescence imager that delivers exceptional sensitivity and outstanding versatility by combining, within a single instrument, the ability to operate in either an open environment or a closed enclosure.
It can be used for fluorescence-guided surgery in both small and large animals, thanks to its flexible configuration featuring either an open optical head or a closed system. The instrument is available in both NIR-I and NIR-II versions.
Its high sensitivity is achieved through laser excitation, patented real-time background subtraction, and visible-light image overlay, enabling reliable performance in a wide range of lighting conditions. In its NIR-II configuration, paired with the high-end Alizé 1.7 InGaAs scientific camera, the system delivers low noise, high efficiency, and rapid image acquisition.
Technology
Category
A Growing Spectrum of Solutions
Overview of Key Features and Applications
Vascular imaging in mouse after injection of NIR-II fluorescent nanoparticles
Commonly Used Fluorophores
- Cy5, Cy5.5, Cy7
- IRDye 700 and IRDye 800 from LiCOR
- Indocyanine Green (ICG)
- ZW 800
- Rare earth (lanthanides), quantum dots and various fluorescent nanoparticles
- The various IVISense fluorescent agents (680, 700, 800)
- Alexa Fluor AF 680, AF 700, AF 750, AF 790
- Infrared fluorescent protein: iRFP
Near infrared fluorescence and NIR-II fluorescence
- Limited autofluorescence
- Great depth penetration
- Better resolution
NIR-II fluorescence (900 to 1650 nm)
- Virtually no autofluorescence
- Imaging through skull, bone, melanin (melanoma studies)
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